endosergЭндокринная хирургияEndocrine Surgery2306-35132310-3965Типография «Печатных дел Мастер»10.14341/serg12711endoserg-12711Research ArticleКлинические случаиCase reportsПервичная лейомиосаркома надпочечника: клинический случай и обзор литературыPrimary adrenal leiomyosarcoma: clinical case and literature reviewhttps://orcid.org/0000-0002-3317-0108ЛукьяновС. В.LukyanovS. V.

Лукьянов Станислав Викторович, к.м.н., доцент, elibrary SPIN: 4181-8431

Stanislav V. Lukyanov, MD, PhD, assistant professor, elibrary SPIN: 4181-8431

svluk@rambler.ruhttps://orcid.org/0000-0001-5889-7138БликянК. М.BlikyanK. M.

Бликян Карина Михайловна, к.м.н., Россия, 344022, Ростов-на-Дону, пер. Нахичеванский, д. 29, elibrary SPIN: 9918-5979

Karina M. Blikyan, MD, PhD, 29 Nahichevansky av., Rostov-on-Don, Russia, elibrary SPIN: 9918-5979

blikjankarina@mail.ruhttps://orcid.org/0000-0001-8476-5606ТодоровС. С.TodorovS. S.

Тодоров Сергей Сергеевич, д.м.н., доцент, Scopus author ID: 7005217473, elibrary SPIN: 4404-3176

Sergey S. Todorov, MD, PhD, assistant professor, Scopus author ID: 7005217473, elibrary SPIN: 4404-3176

sertodorov@gmail.comhttps://orcid.org/0000-0003-4541-6707ДерибасВ. Ю.DeribasV. Y.

Дерибас Виктория Юрьевна, ассистент, Scopus author ID: 57217475386, elibrary SPIN: 8700-5205

Viktoriya Y. Deribas, assistant, Scopus author ID: 57217475386, elibrary SPIN: 8700-5205

derbasv@gmail.comhttps://orcid.org/0000-0002-4691-417XЛукьяновН. С.LukyanovN. S.

Лукьянов Никита Станиславович, старший лаборант 

Nikita S. Lukyanov

lukrus61@gmail.comРостовский государственный медицинский университетРоссияRostov State Medical UniversityRussian Federation2021270920211513642Copyright © Лукьянов С.В., Бликян К.М., Тодоров С.С., Дерибас В.Ю., Лукьянов Н.С., 20212021Лукьянов С.В., Бликян К.М., Тодоров С.С., Дерибас В.Ю., Лукьянов Н.С.Lukyanov S.V., Blikyan K.M., Todorov S.S., Deribas V.Y., Lukyanov N.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.surg-endojournals.ru/jour/article/view/12711

Лейомиосаркома надпочечника – это редкая мезенхимиальная опухоль надпочечников, диагностика которой происходит чаще всего после того, как она достигает больших размеров. Первичная лейомиосаркома надпочечников встречается крайне редко: в англоязычной литературе ранее сообщалось только о 45 клинических наблюдениях. Мы представляем клинический случай 46-летнего мужчины с образованием правого надпочечника размерами 12х8х7,5 см. Пациенту было проведено оперативное вмешательство в объеме правосторонняя адреналэктомия, нефрэктомия, пластика нижней полой вены. Фенотип подтвержден световой микроскопией и иммуногистохимией. Микроскопическое исследование опухоли представлено из веретеновидных и полиморфных клеток, формирующих разнонаправленные пучковые структуры, имеющие высокую скорость митоза. Иммуногистохимически опухолевые клетки оказались положительны на актин гладких мышц, СD - 34, CD – 117.

Adrenal leiomyosarcoma — rare mesenchymal tumor, which is diagnosed most often after it reaches a large size. Primary adrenal leiomyosarcoma is extremely rare: in the English-language literature, only 45 cases were previously reported. We report the case of a 46-year-old man with the formation of the right adrenal gland measuring 12x8x7,5 cm. The patient underwent right-sided adrenalectomy, nephrectomy, and plastic of the inferior vena cava. The phenotype was confirmed by light microscopy and immunohistochemistry. Microscopic examination of the tumor is represented by fusiform and polymorphic cells that form multidirectional bundle structures with a high rate of mitosis. Immunohistochemically, tumor cells were positive for smooth muscle actin, CD-34, CD-117.

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The authors declare that there are no conflicts of interest present.