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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">endoserg</journal-id><journal-title-group><journal-title xml:lang="ru">Эндокринная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Endocrine Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-3513</issn><issn pub-type="epub">2310-3965</issn><publisher><publisher-name>Типография «Печатных дел Мастер»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/serg9950</article-id><article-id custom-type="elpub" pub-id-type="custom">endoserg-9950</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинический случай</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Case</subject></subj-group></article-categories><title-group><article-title>Возможности ПЭТ/КТ с 18F-ФДГ в диагностике гормонально неактивного адренокортикального рака: клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>18F-FDG PET/CT in nonfunctioning adrenocortical carcinoma diagnostics: case report</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3930-5998</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгушин</surname><given-names>Михаил Борисович</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgushin</surname><given-names>Mikhail B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор РАН</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">mdolgushin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6891-9836</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартинович</surname><given-names>Александр Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Martinovich</surname><given-names>Alexander A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог отделения позитронной эмиссионной томографии</p></bio><bio xml:lang="en"><p>MD</p></bio><email xlink:type="simple">alexander_martinovich@msn.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0770-3406</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мещерякова</surname><given-names>Надежда Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Meshcheriakova</surname><given-names>Nadezhda A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">mdnadya@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7226-5129</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тулин</surname><given-names>Павел Евгеньевич</given-names></name><name name-style="western" xml:lang="en"><surname>Tulin</surname><given-names>Pavel E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">480pol@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГБУ &amp;ldquo;Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина&amp;rdquo; Минздрава России&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;N.N. Blokhin National Medical Oncology Research Center&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>21</day><month>05</month><year>2019</year></pub-date><volume>12</volume><issue>4</issue><fpage>196</fpage><lpage>201</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Долгушин М.Б., Мартинович А.А., Мещерякова Н.А., Тулин П.Е., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Долгушин М.Б., Мартинович А.А., Мещерякова Н.А., Тулин П.Е.</copyright-holder><copyright-holder xml:lang="en">Dolgushin M.B., Martinovich A.A., Meshcheriakova N.A., Tulin P.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surg-endojournals.ru/jour/article/view/9950">https://www.surg-endojournals.ru/jour/article/view/9950</self-uri><abstract><p>Клиническое наблюдение больного с рецидивом адренокортикального рака после адреналэктомии и последующего комплексного лечения.</p><p>У мужчины 46 лет было выявлено объемное образование надпочечника. При исследовании гормонального профиля активность образования исключена. Ввиду местнораспространенного процесса пациенту было проведено радикальное лечение. Спустя 5 лет после хирургического лечения выявлен местный рецидив заболевания по результатам КТ. Для уточнения распространенности процесса пациенту выполнена ПЭТ/КТ с 18F-ФДГ, по результатам которой отдаленных метастазов выявлено не было. После проведения пациенту комплексной терапии и периода наблюдения повторно выполнена ПЭТ/КТ, диагностирован диссеминированный процесс. Данное клиническое наблюдение демонстрирует, что ПЭТ/КТ с 18F-ФДГ позволяет уточнить природу объемных образований надпочечников, выявляя признаки их злокачественности, и является ценным инструментом при адренокортикальном раке в случаях рестадирования, при подозрениях на рецидив заболевания и в диагностике метастатического поражения.</p></abstract><trans-abstract xml:lang="en"><p>Clinical observation of the patient with adrenocortical cancer recurrence after adrenalectomy and multiple treatment.</p><p>A 46 year old man was diagnosed with adrenal mass. Endocrine activity was excluded. Due to local cancer advancement, the patient was given a radical treatment. After 5 years after surgical treatment, a local recurrence of the disease was detected according to the results of CT. For further restaging the patient underwent PET/CT with 18F-FDG, according to the results no distant metastases were detected. After complex treatment and observation period metastases were diagnosed. This clinical observation demonstrates possibilities of PET/CT with 18F-FDG – PET/CT, helps to determine nature of adrenal mass formations, revealing signs of their malignancy and is a valuable tool in adrenocortical cancer in cases of recurrent disease and in cases of metastatic lesions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>клинический случай</kwd><kwd>ПЭТ/КТ</kwd><kwd>18F-ФДГ</kwd><kwd>адренокортикальный рак</kwd><kwd>рецидив</kwd></kwd-group><kwd-group xml:lang="en"><kwd>case report</kwd><kwd>PET/CT</kwd><kwd>18F-FDG</kwd><kwd>adrenocortical cancer</kwd><kwd>recurrence</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Roman S. Adrenocortical carcinoma. Curr Opin Oncol. 2006;18(1):36-42. doi: https://doi.org/10.1097/01.cco.0000198976.43992.14.</mixed-citation><mixed-citation xml:lang="en">Roman S. Adrenocortical carcinoma. 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