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Syndrome of inappropriate secretion of antidiuretic hormone in the practice of endocrinologist

https://doi.org/10.14341/serg12692

Abstract

Hyponatremia is the most common disorder of water and electrolyte balance encountered in clinical practice. Conditions associated with hyponatremia require hospitalization in 15–20% of cases. Hyponatremia is a predictor of poor outcome in a wide range of diseases and therefore requires an interdisciplinary approach. This problem leads to an increase in complications and the length of hospital stay and mortality. The review focuses on the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), which accounts for approximately one third of all cases of hyponatremia and is more common in endocrinology than other fluid and electrolyte disorders along with central diabetes insipidus. The article presents modern approaches to the treatment of SIADH based on international clinical guidelines.

About the Authors

Agunda V. Dzagaxova
Endocrinology Research Centre
Russian Federation

Agunda Vladimirovna Dzagakhova - Clinical resident; eLibrary SPIN: 5326-7600.

Moscow


Competing Interests:

not



Nino N. Katamadze
Endocrinology Research Centre
Russian Federation

Nino Nikolaevna Katamadze - clinical resident, eLibrary SPIN: 6755-9320.

Dmitry Ulyanova street 11 bld 2, 117036 Moscow


Competing Interests:

not



Ekaterina A. Pigarova
Endocrinology Research Centre
Russian Federation

Ekaterina Aleksandrovna Pigarova - MD, PhD; eLibrary SPIN: 6912-6331; Scopus Author ID: 55655098500; Researcher ID: T-9424-2018.

Moscow


Competing Interests:

not



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Supplementary files

1. Figure 1. Scheme of antidiuretic hormone action in the distal nephron
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Type Исследовательские инструменты
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Dzagaxova A.V., Katamadze N.N., Pigarova E.A. Syndrome of inappropriate secretion of antidiuretic hormone in the practice of endocrinologist. Endocrine Surgery. 2020;14(3):4-12. (In Russ.) https://doi.org/10.14341/serg12692

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