Intraoperative identification of parathyroid glands during endocrine surgery
https://doi.org/10.14341/serg12724
Abstract
Nowadays, diabetes and diseases of thyroid gland take place on the first two stage in the rank of all endocrine diseases. There are 3 directions to treat thyroid glands pathologies such as: using special pills which substitute natural thyroid hormones, surgery and radioiodine therapy. It has proven that surgery of thyroid gland is the most effective method among considering upper. at The same time, it is associated with the greatest risks of complications. The most common injuries are damage to the recurrent laryngeal nerve and unintentional traumatization or removal of a healthy parathyroid gland. Parathyroid gland is a critical organ during thyroid surgery. It means that all negative reaction nearby the structure can lead to development different complications: hypoparathyroidism (transient or chronic) and hypocalcemia. In this article is considered actual methods of intraoperative optical visualization of parathyroid glans. The fundamental foundations of such methods, their advantages and disadvantages are also analyzed. It is shown that fluorescent methods in the red and near infrared regions of the spectrum using exogenous dyes have essential importance for endocrine surgery, as they allow to improve identification and reduce the risk of postoperative complications.
About the Authors
A. A. Bubnov
National Research Nuclear University «MEPhI», Engineering Physics Institute of Biomedicine;
Endorcinology Research Center
Russian Federation
Russian Federation
Alexander A. Bubnov, postgraduate student, medical physicist
11 Dmitriya Ulianova str., 117292, Moscow
eLibrary SPIN-код: 9380-1293
K. Yu. Slashchuk
Endorcinology Research Center
Russian Federation
Russian Federation
Konstantin Y. Slashchuk, MD, Cand. Sci. (Med)]
Moscow
eLibrary SPIN-код: 3079-8033
E. A. Shirshin
Lomonosov Moscow State University
Russian Federation
Russian Federation
Evgeny A. Shirshin, Cand. Sci., senior researcher
Moscow
eLibrary SPIN-код: 9159-1676
V. Yu. Timoshenko
National Research Nuclear University «MEPhI», Engineering Physics Institute of Biomedicine;
Lomonosov Moscow State University
Russian Federation
Russian Federation
Victor Yu Timoshenko, Dr. Sci., professor
Moscow
eLibrary SPIN-код: 7536-2368
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Supplementary files
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1. Figure 1. The number of cases of intraoperative PTG fluorescence imaging in thyroidectomy (according to Scopus, search for: Intraoperative AND Imaging OR Identification AND Parathyroid AND Thyroidectomy). | |
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2. Figure 2. a — photograph of the thyroid gland during surgery: 1 — normal tissue; 2 — node; 3 — node capsule; b — typical light reflection spectra for thin sections of thyroid tissue with nodules. | |
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3. Figure 3 Examples of images of PTG with ICG injection. a — visualization in white light; b — fluorescent imaging in the infrared range. | |
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| Type | Исследовательские инструменты | |
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Review
For citations:
Bubnov A.A., Slashchuk K.Yu., Shirshin E.A., Timoshenko V.Yu. Intraoperative identification of parathyroid glands during endocrine surgery. Endocrine Surgery. 2021;15(3):41-47. (In Russ.) https://doi.org/10.14341/serg12724
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