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Эндокринная хирургия

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Интраоперационное определение паратгормона в стратегии хирургического лечения первичного гиперпаратиреоза

https://doi.org/10.14341/2306-3513-2011-2-18-25

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Аннотация

Задача хирургического лечения больных с первичным гиперпаратиреозом (ПГПТ) – нормализация уровня паратгормона (ПТГ) и кальция после операции. Ни один из методов дооперационной диагностики не позволяет достоверно определить оптимальный объем оперативного вмешательства в каждом конкретном случае, в связи с чем принято выполнять билатеральную интраоперационную ревизию зон типичного расположения околощитовидных желез. С появлением метода определения интактного ПТГ во время операции стало возможным оценить адекватность хирургического вмешательства уже на операционном столе. Кроме того, этот метод позволяет минимизировать операционную травму и длительность хирургического вмешательства, а также широко использовать видеоассистированные методы в лечении ПГПТ. Был выполнен ретроспективный анализ результатов интраоперационного определения ПТГ у 230 больных с ПГПТ. В зависимости от успешности оперативного вмешательства все больные разделены на 4 группы соответственно полученным результатам кони дискордантности исследования. Анализ результатов показал высокую чувствительность (93,3%), высокую специфичность (85,7%) и высокую предсказательную ценность положительного результата (99,5%) интраоперационного определения уровня ПТГ, что позволяет ориентироваться при выборе операционной стратегии в хирургическом лечении ПГПТ.

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Для цитирования:


., ., . Интраоперационное определение паратгормона в стратегии хирургического лечения первичного гиперпаратиреоза. Эндокринная хирургия. 2011;5(2):18-25. https://doi.org/10.14341/2306-3513-2011-2-18-25

For citation:


Kuznetsov N.S., Kim I.V., Kuznetsov S.N. Intraoperative parathyroid hormone in strategy of surgical treatment of a primary hyperparathyreosis. Endocrine Surgery. 2011;5(2):18-25. (In Russ.) https://doi.org/10.14341/2306-3513-2011-2-18-25

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