Clinical case of indolent primary medullary cancer
https://doi.org/10.14341/serg12713
Abstract
Medullary thyroid cancer (MRSH) has a high malignant potential in the vast majority of cases, but in some patients with MRSH is characterized by a sluggish, non-aggressive course, when patients with the presence of proven medullary carcinoma or distant metastases and / or relapse, can live without progression for a sufficiently long time. Such a course of a malignant tumor is called indolent. The article presents a clinical case of diagnosis and treatment of indolent primary MRSH in a patient with a duration of the disease of 11 years. Shows some features of the dynamics of the level of basal calcitonin and cancer-embryonic antigen (CEA), ultrasound characteristics and data of fine-needle puncture biopsy of the tumor. The phenomenon of indolent course of MRSH characterized, as a rule, by a high malignant potential, is probably due to the biological characteristics of the tumor and requires further research.
About the Authors
S. V. Miroshnikov
Orenburg State Medical University; Orenburg Regional Clinical Hospital № 2
Russian Federation
Russian Federation
Sergey V. Miroshnikov MD, PhD
Orenburg district, Nezhinka, 42 Tenistaya street, 460053
Orenburg
D. B. Demin
Orenburg State Medical University
Russian Federation
Russian Federation
Dmitriy B. Demin, MD, PhD, Professor
A. I. Belyaeva
Orenburg State Medical University
Alexandra I. Belyaeva, clinical resident of the Department of Surgery OrGMU]
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1. Fig. 1. Ultrasound picture of medullary thyroid cancer of patient Sh. (hypoechoic, uneven contours, microcalcifications (TIRADS-5)). | |
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2. Fig. 2. Gross specimen (tumor node size). | |
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3. Fig. 3. Gross specimen (thyroid gland with a tumor node and pretracheal tissue with lymph nodes). | |
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For citations:
Miroshnikov S.V., Demin D.B., Belyaeva A.I. Clinical case of indolent primary medullary cancer. Endocrine Surgery. 2021;15(2):22-26. (In Russ.) https://doi.org/10.14341/serg12713
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