Persistent primary hyperparathyroidism in parathyroid glands ectopic to the mediastinum (clinical observation and long-term results)

первичный гиперпаратиреоз, паратиреоидэктомия, резидуальная паратирома, эктопия околощитовидной железы, верхнее средостение, аортопульмональное окно, персистирующий гиперпаратиреоз, консервативное лечение, витамин D

1. Dedov II, Melnichenko GA, Mokrysheva NG, et al. Primary hyperparathyroidism: the clinical picture, diagnostics, differential diagnostics, and methods of treatment. Problems of Endocrinology. 2016;62(6):40-77. (In Russ.). doi: https://doi.org/10.14341/probl201662640-77

2. Mokrysheva NG, Mirnaya SS, Dobreva EA, et al. Primary hyperparathyroidism in Russia according to the registry. Problems of Endocrinology. 2019;65(5):300-310. (In Russ.). doi: https://doi.org/10.14341/probl10126

3. Minisola S. Primary hyperparathyroidism is one of the three most frequent endocrine disorders, typically diagnosed in the years following menopause and with advancing age. J Endocrinol Invest. 2012;35(7):1.

4. Wermers RA, Khosla S, Atkinson EJ, et al. Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993–2001: an update on the changing epidemiology of the disease. J Bone Miner Res. 2006;21(1):171-177. doi: https://doi.org/10.1359/JBMR.050910

5. Davydov MI, Aksel’ EM. Statistika zlokachestvennykh novoobrazovanii v Rossii i stranakh SNG v 2008 g. Vestnik RONTs im. N.N. Blokhina RAMN. 2009;21(2): pril. 2. (In Russ.).

6. Travis WD, Brambilla E, Burke AP, et al. WHO classification of tumours of the lung, pleura, thymus and heart. 4th edn. Lyon: International Agency for Research on Cancer; 2015.

7. Пищик В.Г., Яблонский П.К. Алгоритмы дифференциальной диагностики новообразований средостения // Вестник СПб университета. — 2008. — №2. — С. 101-108. [Pishchik VG, Iablonskii PK. Algoritmy differentsial’noi diagnostiki novoobrazovanii sredosteniia. Vestnik SPb universiteta. 2008;(2):101-108. (In Russ.).

8. Chikinev IuV, Drobiazgin EA, Anikeeva OIu, et al. Diagnostika i lechenie opukholei sredosteniia. Sibirskii nauchnyi meditsinskii zhurnal. 2014;34(4):109-114. (In Russ.).

9. Ilyicheva EA, Bersenev GA, Grigoryev EG. Spontaneous rupture of the parathyroid adenoma with formation cervico-retrosternal cyst and massive hematoma: a case report. Endocrine Surgery. 2021;15(2):27-33. (In Russ.). doi: https://doi.org/10.14341/serg12708

10. Bilezikian JP, Brandi ML, Eastell R, et al. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the fourth international workshop. J Clin Endocrinol Metab. 2014;99(10):3561-3569. doi: https://doi.org/10.1210/jc.2014-1413

11. Dedov II, Mel’nichenko GA, Belaia ZE, Rozhinskaia LI. Osteoporosis: from a rare symptom of endocrine diseases to the tacit epidemic of XX-XXI centuries. Problems of Endocrinology. 2011;57(1):35-45. (In Russ.). doi: https://doi.org/10.14341/probl201157135-45

12. Yanevskaya LG, Karonova TL, Sleptsov IV, et al. Primary hyperparathyroidism: clinical forms and their features. Retrospective study. Clinical and experimental thyroidology. 2019;15(1):19-29. (In Russ.). doi: https://doi.org/10.14341/ket10213

13. Kudashkina EY, Gavrilenko EG, Yakushev AA, et al. Primary hyperparathyroidism with a predominant lesion of the gastrointestinal tract. Russ Arch Intern Med. 2021;11(1):51-59. (In Russ.). doi: https://doi.org/10.20514/2226-6704-2021-11-1-51-59

14. Pinskii SB, Tsmailo VM, Fedorova OA. Oshibki i trudnosti v diagnostike i lechenii pervichnogo giperparatireoza. Sibirskii meditsinskii zhurnal. 2008;(4):23-27. (In Russ.).

15. Bilezikian JP. Primary hyperparathyroidism. J Clin Endocrinol Metab. 2018;103(11):3993-4004. doi: https://doi.org/10.1210/jc.2018-01225

16. Bilezikian JP, Khan AA, Silverberg SJ, et al. Evaluation and management of primary hyperparathyroidism: summary statement and guidelines from the fifth international workshop. J Bone Miner Res. 2022;37(11):2293-2314. doi: https://doi.org/10.1002/jbmr.4677

17. Dedov II, Melnichenko GA, Mokrysheva NG, et al. Draft of clinical guidelines for the diagnosis and treatment of primary hyperparathyroidism in adult patients. Endocrine Surgery. 2023;16(4):5-54. (In Russ.). doi: https://doi.org/10.14341/serg12790

18. Kalinin AP, Kotova IV, Britvin TA, et al. Hypercalcemic crisis. Alm Clin Med. 2016;16(32):101-104. doi: https://doi.org/10.18786/2072-0505-2014-32-101-104

19. McMahon DJ, Carrelli A, Palmeri N, et al. Effect of parathyroidectomy upon left ventricular mass in primary hyperparathyroidism: A meta-analysis. J Clin Endocrinol Metab. 2015;100(12):4399-4407. doi: https://doi.org/10.1210/jc.2015-3202

20. Zanocco KA, Wu JX, Yeh MW. Parathyroidectomy for asymptomatic primary hyperparathyroidism: A revised cost-effectiveness analysis incorporating fracture risk reduction. Surgery. 2017;161(1):16-24. doi: https://doi.org/10.1016/j.surg.2016.06.062

21. Seib CD, Chomsky-Higgins K, Gosnell JE, et al. Patient frailty should be used to individualize treatment decisions in primary hyperparathyroidism. World J Surg. 2018;42(10):3215-3222. doi: https://doi.org/10.1007/s00268-018-4629-3

22. Kebebew E, Clark OH. Parathyroid adenoma, hyperplasia, and carcinoma. Surg Oncol Clin N Am. 1998;7(4):721-748. doi: https://doi.org/10.1016/S1055-3207(18)30242-4

23. Singh Ospina NM, Rodriguez-Gutierrez R, Maraka S, et al. Outcomes of parathyroidectomy in patients with primary hyperparathyroidism: A systematic review and meta-analysis. World J Surg. 2016;40(10):2359-2377. doi: https://doi.org/10.1007/s00268-016-3514-1

24. Fancy T, Gallagher D 3rd, Hornig JD. Surgical anatomy of the thyroid and parathyroid glands. Otolaryngol Clin North Am. 2010;43(2):221-227. doi: https://doi.org/10.1016/j.otc.2010.01.001

25. Vetshev PS, Ablitsov AIu, Zhivotov VA, et al. Khirurgicheskoe lechenie pervichnogo giperparatireoza s redkoi ektopiei adenomy okoloshchitovidnoi zhelezy. Vestnik Natsional’nogo mediko-khirurgicheskogo Tsentra im. NI. Pirogova. 2018;(3):58-61. (In Russ.).

26. Ilyicheva EA, Ayusheeva AV, Makhutov VN, et al. Surgical treatment of persistent tertiary hyperparathyroidism induced by parathyroid adenomas in the aortopulmonary window. Endocr Surg. 2014;8(3):27-34. (In Russ.). doi: https://doi.org/10.14341/serg2014327-34

27. Phitayakorn R, McHenry CR. Incidence and location of ectopic abnormal parathyroid glands. Am J Surg. 2006;191(3):418-423. doi: https://doi.org/10.1016/j.amjsurg.2005.10.049

28. Iihara M, Suzuki R, Kawamata A, et al. Thoracoscopic removal of mediastinal parathyroid lesions: selection of surgical approach and pitfalls of preoperative and intraoperative localization. World J Surg. 2012;36(6):1327-1334. doi: https://doi.org/10.1007/s00268-011-1404-0

29. Taterra D, Wong LM, Vikse J, et al. The preva-lence and anatomy of parathyroid glands: a meta-analysis with implications for parathyroid surgery. Langenbecks Arch Surg. 2019;404(1):63-70. doi: https://doi.org/10.1007/s00423-019-01751-8

30. Noussios G, Anagnostis P, Natsis K. Ectopic parathyroid glands and their anatomical, clinical and surgical implications. Exp Clin Endocrinol Diabetes. 2012;120(10):604-610. doi: https://doi.org/10.1055/s-0032-1327628

31. Romashchenko PN, Fomin NF, Maistrenko NA, et al. Clinical and anatomical rationale of minimally invasive parathyroid surgery. Tavricheskiy Med Vestn. 2020;23(2):155-164. (In Russ.). doi: https://doi.org/10.37279/2070-8092-2020-23-2-155-164

32. Porkhanov VA, Kononenko VB, Bodnia VN, et al. Diagnosticheskaia rol’ videotorakoskopii pri patologii sredosteniia. Kuban Scientific Medical Bulletin. 1999;(7):67-70. (In Russ.).

33. Solorzano CC, Carneiro-Pla D. Minimizing cost and maximizing success in the preoperative localization strategy for primary hyperparathyroidism. Surg Clin North Am. 2014;94(3):587-605. doi: https://doi.org/10.1016/j.suc.2014.02.006

34. Ryabov AB, Pikin OV, Aleksandrov OA, et al. Diagnostic clinical algorithm for mediastinal tumors. Khirurgiya Zhurnal im NI Pirogova. 2022;23(5):43-51. (In Russ.). doi: https://doi.org/10.17116/hirurgia202205143

35. Lee SW, Shim SR, Jeong SY, Kim SJ. Direct comparison of preoperative imaging modalities for localization of primary hyperparathyroidism: A systematic review and network metaanalysis. JAMA Otolaryngol Head Neck Surg. 2021;147(8):692-706. doi: https://doi.org/10.1001/jamaoto.2021.0915

36. Broos WAM, Wondergem M, Knol RJJ, van der Zant FM. Parathyroid imaging with 18F-fluorocholine PET/CT as a firstline imaging modality in primary hyperparathyroidism: a retrospective cohort study. EJNMMI Res. 2019;9(1):72. doi: https://doi.org/10.1186/s13550-019-0544-3

37. Piccardo A, Bottoni G, Boccalatte LA, et al. Head-to-head comparison among 18F-choline PET/CT, 4D contrast-enhanced CT, and 18F-choline PET/4D contrast-enhanced CT in the detection of hyperfunctioning parathyroid glands: a systematic review and meta-analysis. Endocrine. 2021;74(2): 404-412. doi: https://doi.org/10.1007/s12020-021-02798-8