Features of multiple endocrine neoplasia type 1 the patient 48 years (MEN-1 in a patient of 48)
Abstract
Given the unique observation of atypical MEN1 (mixed version) of a man 48 years old, due to the presence 9 of multiple tumors and hyperplasia in 8 different organs (parathyroid glands, pancreatic and thyroid glands, duodenum, lung, stomach, skin and adrenal glands). The peculiarity of this case is medullary carcinoma of the thyroid gland that is usually associated with the syndrome of MEN2. The patient had typical clinical hypoglycemic syndrome, however, among all the investigated neuroendocrine tumors of the insulinproducing cells were not available, that doesn’t mean there are not revealed (possibly very small) tumors of the pancreas. At the same time, it is known that clinical manifestations of MEN1 may be due to the cumulative effect of all complex of the hormones produced simultaneously by several multiple tumors.
About the Authors
Sergey Vladimirovich Sergуikо
South Ural State Medical University
Russian Federation
MD, PhD, Professor
Russian Federation
MD, PhD, Professor
Valeriy Alekseevich Privalov
South Ural State Medical University
Russian Federation
MD, PhD, Professor
Russian Federation
MD, PhD, Professor
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Review
For citations:
Sergуikо S.V., Privalov V.A. Features of multiple endocrine neoplasia type 1 the patient 48 years (MEN-1 in a patient of 48). Endocrine Surgery. 2015;9(3):49-52. (In Russ.)
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