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Эндокринная хирургия

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Прогностические критерии клинического течения и диагностика медуллярного рака щитовидной железы

https://doi.org/10.14341/serg201344-13

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Аннотация

Проведено ретроспективно-проспективное клиническое аналитическое исследование 137 пациентов с медулляр- ным раком щитовидной железы (МРЩЖ). Выявлена крайне низкая 35%-ная чувствительность тонкоигольной аспи- рационной биопсии и высокая чувствительность исследования уровня базального кальцитонина в диагностике МРЩЖ. Представлены результаты изучения спектра герминальных и спорадических мутаций генов RET и RAS на российской популяции, доказано влияние вида мутации на агрессивность течения МРЩЖ.

Об авторах

D Gazizova

аспирант ФГБУ ЭНЦ


D Beltsevich

доктор мед. наук, гл. науч. сотр. отд. хирургии ФГБУ ЭНЦ


A Tiulpakov

доктор мед. наук, зав. отделением наследственных эндокринопатий ФГБУ ЭНЦ


T Soldatova

канд. мед. наук, зав. отделением ультразвуковой диагностики ФГБУ ЭНЦ


A Ilyin

зав. отделением клинической биохимии ФГБУ ЭНЦ


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Для цитирования:


., ., ., ., . Прогностические критерии клинического течения и диагностика медуллярного рака щитовидной железы. Эндокринная хирургия. 2013;7(4):4-13. https://doi.org/10.14341/serg201344-13

For citation:


Gazizova D.O., Beltsevich D.G., Tiulpakov A.N., Soldatova T.V., Ilyin A.V. Diagnosis of medullary thyroid cancer and prognostic factors of disease aggressiveness. Endocrine Surgery. 2013;7(4):4-13. (In Russ.) https://doi.org/10.14341/serg201344-13

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