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Well-differentiated thyroid cancer disclosed during pregnancy. Management experience

https://doi.org/10.14341/serg2015432-38

Abstract

Thyroid cancer have the second place as malignancy detectable during pregnancy. Disclose of thyroid cancer during pregnancy raises many questions among endocrinologists, oncologists and obstetricians. Our aim was to analyze the results of delayed treatment in 15 women with differentiated thyroid cancer diagnosed during pregnancy. Our experience shows that in absence of progression of locally advanced differentiated thyroid cancer during pregnancy the observation tactics with deferred surgical treatment after delivery is reasonable, which is not worsening early and late results of delayed treatment.

About the Authors

A. A. Ilyin
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD, PhD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


P. O. Rumyantsev
Endocrinology Research Centre
Russian Federation
MD, PhD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


D. N. Derbugov
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


D. N. Semin
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


N. V. Severskaya
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD, PhD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


P. A. Isaev
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD, PhD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


S. V. Vasilkov
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


V. S. Medvedev
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD, PhD, Professor
Competing Interests: Автор декларируют отсутствие конфликта интересов.


V. V. Polkin
Tsyb Medical Radiological Research Centre, National Medical Research Radiological Centre
Russian Federation
MD, PhD
Competing Interests: Автор декларируют отсутствие конфликта интересов.


References

1. Smith LH, Danielsen B, Allen ME, Cress R. Cancer associated with obstetric delivery: results of linkage with the California cancer registry. Am J Obstet Gynecol. 2003;189(4):1128-1135. doi: 10.1067/S0002-9378(03)00537-4.

2. Rosene-Montella K. Medical Management of the Pregnant Patient. A Clinician’s Handbook. New York: Springer; 2015. doi: 10.1007/978-1-4614-1244-1.

3. Vini L, Hyer S, Pratt B, Harmer C. Management of differentiated thyroid cancer diagnosed during pregnancy. Eur J Endocrinol. 1999;140(5):404-406. doi: 10.1530/eje.0.1400404.

4. Cabezon CA, Carrizo LC, Costanzo PR. Evolution of differentiated thyroid cancer during pregnancy in a community University Hospital in Buenos Aires, Argentina. Arq Bras Endocrinol Metabol. 2013;57(4):307-311. doi: 10.1590/S0004-27302013000400005.

5. Budak A, Gulhan I, Aldemir OS, et al. Lack of influence of pregnancy on the prognosis of survivors of thyroid cancer. Asian Pac J Cancer Prev. 2013;14(11):6941-6943. doi: 10.7314/APJCP.2013.14.11.6941.

6. Messuti I, Corvisieri S, Bardesono F, et al. Impact of pregnancy on prognosis of differentiated thyroid cancer: clinical and molecular features. Eur J Endocrinol. 2014;170(5):659-666. doi: 10.1530/EJE-13-0903.

7. Hirsch D, Levy S, Tsvetov G, et al. Impact of pregnancy on outcome and prognosis of survivors of papillary thyroid cancer. Thyroid. 2010;20(10):1179-1185. doi: 10.1089/thy.2010.0081.

8. Zamora-Ros R, Rinaldi S, Biessy C, et al. Reproductive and menstrual factors and risk of differentiated thyroid carcinoma: the EPIC study. Int J Cancer. 2015;136(5):1218-1227. doi: 10.1002/ijc.29067.

9. Cao Y, Wang Z, Gu J, et al. Reproductive Factors but Not Hormonal Factors Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis. Biomed Res Int. 2015;2015:103515. doi: 10.1155/2015/103515.

10. Walshe P, Seaberg RM, Yehuda M, Freeman J. Management of medullary carcinoma of the thyroid during pregnancy in a patient with an intron substitution. J Otolaryngol Head Neck Surg. 2008;37(2):E39-41.

11. Sarathi V, Bandgar TR, Menon PS, Shah NS. Pheochromocytoma and medullary thyroid carcinoma in a pregnant multiple endocrine neoplasia-2A patient. Gynecol Endocrinol. 2011;27(8):533-535. doi: 10.3109/09513590.2010.507285.

12. Muzannara MA, Tawfeeq N, Nasir M, et al. Vaginal delivery in a patient with pheochromocytoma, medullary thyroid cancer, and primary hyperparathyroidism (multiple endocrine neoplasia type 2A, Sipple's syndrome). Saudi J Anaesth. 2014;8(3):437-439. doi: 10.4103/1658-354X.136652.

13. Vannucchi G, Perrino M, Rossi S, et al. Clinical and molecular features of differentiated thyroid cancer diagnosed during pregnancy. Eur J Endocrinol. 2010;162(1):145-151. doi: 10.1530/EJE-09-0761.

14. Shindo H, Amino N, Ito Y, et al. Papillary thyroid microcarcinoma might progress during pregnancy. Thyroid. 2014;24(5):840-844. doi: 10.1089/thy.2013.0527.

15. Duntas LH. Clinical comments related to medullary thyroid cancer diagnosis and management. Thyroid Res. 2013;6 Suppl 1:S6. doi: 10.1186/1756-6614-6-S1-S6.


Supplementary files

1. Таблица 1
Subject Рак щитовидной железы; беременность
Type Таблица данных
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For citations:


Ilyin A.A., Rumyantsev P.O., Derbugov D.N., Semin D.N., Severskaya N.V., Isaev P.A., Vasilkov S.V., Medvedev V.S., Polkin V.V. Well-differentiated thyroid cancer disclosed during pregnancy. Management experience. Endocrine Surgery. 2015;9(4):32-38. (In Russ.) https://doi.org/10.14341/serg2015432-38

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