18F-FDG PET/CT in nonfunctioning adrenocortical carcinoma diagnostics: case report
https://doi.org/10.14341/serg9950
Abstract
Clinical observation of the patient with adrenocortical cancer recurrence after adrenalectomy and multiple treatment.
A 46 year old man was diagnosed with adrenal mass. Endocrine activity was excluded. Due to local cancer advancement, the patient was given a radical treatment. After 5 years after surgical treatment, a local recurrence of the disease was detected according to the results of CT. For further restaging the patient underwent PET/CT with 18F-FDG, according to the results no distant metastases were detected. After complex treatment and observation period metastases were diagnosed. This clinical observation demonstrates possibilities of PET/CT with 18F-FDG – PET/CT, helps to determine nature of adrenal mass formations, revealing signs of their malignancy and is a valuable tool in adrenocortical cancer in cases of recurrent disease and in cases of metastatic lesions.
About the Authors
Mikhail B. DolgushinN.N. Blokhin National Medical Oncology Research Center
Russian Federation
MD, PhD, Professor
Alexander A. Martinovich
N.N. Blokhin National Medical Oncology Research Center
Russian Federation
MD
Nadezhda A. Meshcheriakova
N.N. Blokhin National Medical Oncology Research Center
Russian Federation
MD, PhD
Pavel E. Tulin
N.N. Blokhin National Medical Oncology Research Center
Russian Federation
MD, PhD
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1. Fig. 1. Recurrence of adrenocortical cancer after adrenalectomy. PET / CT scan with 18F-FDG. PET (MIP) in frontal projection (a), CT scan with intravenous contrast enhancement (b), PET- (c) and PET / CT- (d) images in axial projection. The arrows mark the volume formation in the bed of the left adrenal gland with signs of marked accumulation of radiopharmaceuticals (SUVmax 33.27). | |
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2. Fig. 2. Progression of adrenocortical cancer with metastatic lesions of the liver, lungs and inside the thoracic lymph nodes. Condition after hemihepatectomy. PET / CT scan with 18F-FDG. PET (MIP) in frontal projection (a), CT scan with intravenous contrast enhancement (b, c), PET (g, e) and PET / CT (e, g) in axial projection. Volume formation in the left adrenal gland (white arrows), metastases (black arrows). | |
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For citations:
Dolgushin M.B., Martinovich A.A., Meshcheriakova N.A., Tulin P.E. 18F-FDG PET/CT in nonfunctioning adrenocortical carcinoma diagnostics: case report. Endocrine Surgery. 2018;12(4):196-201. (In Russ.) https://doi.org/10.14341/serg9950
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